Product Review

Pregnenolone is the starting point from which all steroid hormones are manufactured in our bodies. Its conversion in the body follows different pathways, depending on individual needs. Several clinical studies have demonstrated that pregnenolone may enhance psychomotor performance and decrease fatigue in healthy subjects. Pregnenolone - The Balancing Hormone Pregnenolone - a hormone produced from cholesterol in our adrenal glands, liver, skin, testicles, ovaries, and brain - was the subject of intense interest in the 1940's. Some of the earliest studies, performed by well-known researcher Hans Selye, found it to be helpful in reducing stress and fatigue. Additional studies were conducted throughout the decade, with positive results. Pregnenolone supplementation was found to benefit people who were under excessive stress. It also was reported to support joint and tissue function and to contribute to skin elasticity. Pregnenolone is believed to affect stress levels through its influence on the adrenal glands, which produce more steroid hormones when people are under stress. Pregnenolone may also affect brain chemistry in beneficial ways. It has been found to inhibit the GABA receptors in brain cells - which may result in increased mental alertness. It may also stimulate the NMDA (N-methyl-D-aspartate) receptors, which play an important role in regulating synapses, thus influencing learning and memory. Pregnenolone - The Unique Hormone Much of the current interest in pregnenolone is related to its role as "the grandmother of all steroid hormones". Pregnenolone is the starting point from which all steroid hormones are manufactured in our bodies. As a "hormone balancer", it has the capacity to increase the levels of steroid hormones that are deficient in our bodies and to reduce the levels of excess circulating hormones. Some scientists believe pregnenolone is converted into other hormones only as they are needed by our bodies. The conversion of pregnenolone follows diff