Product Review

Here is some of the research behind the ingredients in Sedorum: Folic Acid - Reports exist of folic acid reducing symptoms associated with restless leg syndrome (RLS) such as numbness, cramps, and paresthesias. Pregnant women have a two to three times increased risk of developing RLS possibly due to deficiency of folic acid and iron. One study showed that reduced serum folic acid levels were correlated with restless legs syndrome in pregnancy and supplementation could minimize these symptoms and promote better sleep Vitamin B12 - A study of nearly 800 seniors showed that vitamin B12 deficiency is common in subjects with neurosensory deficits and RLS. There are some preliminary clinical reports that the cyanocobalamin form of vitamin B12 can help relieve tremor associated with restless leg syndrome. Iron - Low levels of iron are associated with RLS in elderly populations, but occasionally plasma levels may not reflect a deficiency while bone marrow measurements can. A clinical study showed that treatment with iron supplements for 2 months significantly improved the RLS severity score. Research suggests abnormal brain iron metabolism plays a role in dopaminergic systems in the brain, influencing the circadian pattern of RLS, and interfering with sleep. Magnesium and Calcium - Supplementation with magnesium may be useful for treating restless legs syndrome. In some RLS patients, magnesium treatment may decrease the amount of movement and increase the amount of sleep in mild to moderate cases. Magnesium deficiency in patients with RLS demonstrates changes in the EEG patterns observed in sleep such as decreased duration and percentage of restorative REM sleep. Calcium, an essential mineral, is required for optimal absorption and effectiveness of magnesium and contributes to normalized brain and neurological function. Typically, these two should be supplemented together in a 2:1 ratio.