One and Only Live Nitrifying Bacteria removes toxic ammonia and nitrite, instantly working to prevent new tank syndrome by establishing a biological filter in your newly set-up aquarium. Use when setting up a new tank, after...

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Product Review

One and Only Live Nitrifying Bacteria removes toxic ammonia and nitrite, instantly working to prevent new tank syndrome by establishing a biological filter in your newly set-up aquarium. Use when setting up a new tank, after a disease treatment or water changes. 4 oz size for freshwater aquaria up to 60 gallons. One and Only has no sulfur or other offensive odors. Made by the recognized expert in aquarium nitrification and microbiology.

  • Supports new tank setup: Jumpstarts natural cycling so fresh builds and resets reach stable conditions sooner.
  • Stabilizes water quality: Helps maintain consistent parameters by supporting biological filtration in freshwater systems.
  • Natural & easy to use: Powered by naturally occurring organisms—simple shake-and-pour dosing with clear directions.
  • Ideal for freshwater tanks: Works with tropical, planted, and community aquariums; compatible with conditioners and test kits.
  • Part of routine care: Use during setup and after filter cleanings or water changes to refresh conditions and promote clarity.

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