Product Review

AFP-PeptizydeTM was developed in response to customer requests for a high DPP IV-containing enzyme product that did not include fruit-based enzymes such as papain or bromelain. Like PeptizydeTM (which does contain papain), it is a combination of three different proteolytic enzymes isolated from fungal plant sources. Each enzyme has a unique set of peptide bonds it prefers to break, so the combination of these enzymes allows much more efficient means of quickly and thoroughly breaking down (hydrolyzing) proteins to its smaller components. The enzymes in AFP-PeptizydeTM work only on food proteins, not carbohydrates, fats, or other compounds, and do not interfere with medications or other supplements (unless they are also proteins, which is extremely unlikely). AFP-PeptizydeTM may be used in combination with other enzyme products, such as Zyme Prime, No-Fenol or other enzyme products. If undecided as to use Peptizyde or AFP-PeptizydeTM, opt for AFP-Peptizyde due to it having no odor/taste or papain. The aminopeptidase enzyme dipeptidyl peptidase IV, or DPP IV, is able to hydrolyze and inactivate the exorphin peptide, casomorphin and is present in both Peptizyde and AFP-PeptizydeTM. However, for maximal protein breakdown, DPP IV is not useful alone, and should be combined with other proteases with different and less stringent peptide bond specificity. For this reason, AFP-PeptizydeTM contains two other fungal proteases with high activity in acid conditions. These enzymes are present in AFP-PeptizydeTM in high amounts for the purpose of quickly hydrolyzing proteins while the food is still in the stomach.