Product Review

The Original Glutathione Formula (OGF) was formulated by Dr. R.H. Keller to overcome the issues associated with the absorption, production and accumulation of glutathione in the cells of our body. OGF provides the essential amino acid building block, cysteine, required for generation of glutathione. For this reason, OGF contains the essential glutathione building block, N- acetyl cysteine, which is more stable and readily converted to cysteine within the body. OGF also includes multiple ingredients that aid in the generation, preservation and regeneration of glutathione through enhancing the activity of Nrf2. In recent years there has been a growing appreciation for Nrf2 and its role in promoting the expression of several different antioxidants. Due to its involvement in the detoxification of cells, Nrf2 has been referred to as the "master regulator" of the antioxidant response. A number of scientific studies have shown that Nrf2 becomes activated in cells undergoing oxidative stress and leads to profound alterations in gene expression. Specifically, the actions of Nrf2 were responsible for increased expression of several antioxidants including glutathione, SOD and catalase. Collectively, OGF increases the abundance of antioxidants, such as glutathione, SOD and catalase within the cells of our body and aims to reduce the presence of free radicals, reduce oxidative stress and restore overall vitality.