Modic Changes: Understanding Reactive Vertebral Endplate and Marrow Morphology



Back pain is a major source of infirmity and disability worldwide. While there is much that we do not know about the causati...

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Modic Changes: Understanding Reactive Vertebral Endplate and Marrow Morphology



Back pain is a major source of infirmity and disability worldwide. While there is much that we do not know about the causation and treatment of back pain, we do know bony edema of the spine is closely associated with spine pain. Decades ago Dr. Michael Modic identified and categorized the findings of bony endplate changes on MRI into a system that now bears his name: Modic changes. This book takes the reader through the normal anatomy and physiology of the vertebral endplates, marrow, and the intervertebral disc. It reveals the pathogenesis which causes Modic changes, pain, and degeneration. It also teaches the reader how to identify and categorize Modic Types on spinal MRI.

Highlights of this eBook:

It contains high quality illustrations and MRI images intended to enhance understanding.

It has a concise focus on the topic that will allow the reader to understand complicated concepts in a short amount of time, perhaps even in one sitting.

It discusses related findings on MRI: Metastatic disease, vertebral endplate fracture, vertebral hemangioma, and fatty infiltration into bone.

It contains a commentary on the research which points to bacterial infections and Modic 1 changes being a source of lower back pain.

It includes three bonus chapters in the appendices that are essentially an additional ebook: Introduction to Reading MRI, Anatomic Atlas of the Lumbar Spine, and Nomenclature of Disc Derangements. For those struggling to read MRI the appendices are a great resource to help master this skill.


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