Product Review

An Ancient Herb - The Greek herbalist Dioscorides catalogued milk thistle in his list of healing plants for liver conditions, improving bile flow and stimulating digestion.* The Roman author Pliny was of a similar opinion. Indeed, milk thistle (Silybum marianum) extracts have been used as traditional herbal remedies for almost 2000 years and milk thistle is now extensively cultivated as a healing herb. Special Antioxidant Benefits: Silymarin refers to three active flavonoid components of milk thistle: primarily silybin with smaller amounts of silydianin and silychristin. This trio neutralizes toxins and improves liver function.* Its action rests primarily upon the ability to inhibit production and activity of hepatotoxic (liver toxic) compounds. More recent evidence indicates that it benefits the health of several other organs as well. The liver is the primary organ for detoxification. Many toxins are either free radicals, or encourage free radical production and may subsequently interfere with the liver's defenses against free radicals. As a potent antioxidant, silymarin intervenes in free radical generation and protects against many reactive oxygen species. In some measurement systems, silymarin is ten times more effective than vitamin E in preventing unwanted oxidation. The extract also increases the liver's content of the antioxidant enzyme glutathione (GSH) by ~35 percent, and increases the levels of the body's major antioxidant enzyme, superoxide dismutase (SOD). Silymarin also modulates the actions of lipoxygenase in the liver. Lipoxygenase acts upon polyunsaturated fatty acids to produce pro-inflammatory compounds called leukotrienes, which cause damage to liver cell membranes. Silymarin is active against all of these assaults upon liver cell integrity and function. It therefore has direct and indirect antioxidant benefits by elevating the body's own defenses. Research has shown that milk thistle extracts also significantly enhance cellular immune biomarkers