Product Review

A targeted probiotic blend clinically demonstrated to support mood*

Contains 30 single-serving sachets. No refrigeration required.

The gut brain axis refers to the bidirectional communication network between the central and autonomic nervous systems and the intestines. Gut-brain communications are mediated by the immune system, endocrine connections such as the hypothalamic-pituitary-adrenal (HPA) axis, and neural pathways involving the enteric nervous system. The gut microbiota is now known to play a pivotal role in gut brain communications. It is a complex interaction whereas the microbiota engages locally with intestinal cells as well as communicating directly with the central nervous system through neuroendocrine, immune, and metabolic pathways [1] Research into gut brain mechanisms is rapidly expanding our understanding and serves to inform the development of targeted probiotic formulations.*

Reference: [1] Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems Ann Gastroenterol. 2015 Apr-Jun; 28(2): 203-209.