Life-Extension Folate 1000mcg / 1mg - New 180 Tablet Size
Folate is involved in neurotransmitter synthesis and critical enzymatic reactions throughout the body.

Why Choose Life Extension's Optimized Fo...

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Product Review

Life-Extension Folate 1000mcg / 1mg - New 180 Tablet Size
Folate is involved in neurotransmitter synthesis and critical enzymatic reactions throughout the body.

Why Choose Life Extension's Optimized Folate?
✔ 700% more bioavailable than folic acid
✔ Non-GMO
✔ Vegetarian tablets

Unlike other brands that use folic acid, Life Extension's Folate is made from 5-MTHF because it is up to seven times more bioactive.

By depleting excess homocysteine, LifeExtension folate benefits cardiovascular health and nervous system function.

Health benefits
â—† Supports cardiovascular health
â—† Supports neurotransmitter synthesis
â—† Maintains healthy homocysteine levels

Importance of Maintaining Healthy Homocysteine Levels
People with elevated homocysteine levels have a greater risk of cognitive decline. (4)
Unlike folic acid, Life Extension 5-MTHF (in this Optimized Folate supplement) is able to cross the blood-brain barrier, which is especially important for people with cognitive difficulties, to enhance the synthesis of acetylcholine in the brain - the neurotransmitter associated with memory.

Choose Life Extention's Optimized Folate because it is already in the bioactive state, unlike traditional folate.

Add to your cart because you deserve the best folate supplement - 5-MTHF.


4. N Engl J Med. 2002 Feb 14;346(7):476-83.


  • Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Vegetarian Tablets
  • Life Extension's Optimized Folate formula promotes both cardiovascular and cognitive health with 1,700 mcg of folate in the form of 5-MTHF, the metabolically active form of folic acid.
  • Metabolically active form – 5-MTHF, the metabolically active form of folate, is good for your heart and brain health. But not everyone can convert the dietary form of folate (known as folic acid) into 5-MTHF. This supplement provides folate’s 5-MTHF form.
  • Ingredients matter – We use only the finest raw ingredients with the purity and potency you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.
  • Live your healthiest life – We believe the answers to a healthier life are within reach, and that scientific research is the key to getting us there.

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